Triphenylene

Triphenylene

SCHEMBL6233334

N=C=O.N=C=O.N=C=O.c1ccc2c(c1)c1ccccc1c1ccccc21

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.40
PAX8 Q06710 1/20 0.38
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 5/20 0.37
CYP2A6 P11509 2/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 4/20 0.36
HPGD P15428 3/20 0.36
THRB P10828 1/20 0.36
GPR3 P46089 4/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
TNKS O95271 1/20 0.36
PARP1 P09874 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP15 Q460N3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylene SCHEMBL9251630 1.00 HPRT1 (0.40) HPRT1PAX8ALDH1A1HSD17B10CYP2A6
Triphenylene SCHEMBL9343146 0.97 HPRT1 (0.38) HPRT1PAX8ALDH1A1HSD17B10CYP2A6
Triphenylene SCHEMBL10808489 0.94 GPR3 (0.36) HPRT1PAX8ALDH1A1HSD17B10CYP2A6
Chrysene SCHEMBL5095521 0.84 HPRT1 (0.70) HPRT1PAX8ALDH1A1HSD17B10CYP2A6
SCHEMBL9786204 0.82 CYP1A2 (0.37) ALDH1A1HSD17B10CYP2A6CYP1A2HPGD
SCHEMBL11038752 0.80 CYP1A2 (0.39) ALDH1A1HSD17B10CYP2A6TSHRCYP1A2
SCHEMBL9824756 0.80 CYP1A2 (0.68) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29712920 0.80 CYP1A2 (0.68) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL23071449 0.79 CDC25B (0.33) MEN1KMT2AIDO1MAOAMAOB
Naphthalene SCHEMBL687007 0.79 CYP2A6 (0.57) HPRT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7285925-A None JP disclosed
EP-1036790-B1 Perfluoro group-containing compounds and hardened polymer of the same KYOEISHA CHEMICAL CO LTD (JP) 2005-06-01 EP disclosed
EP-1036790-A1 Perfluoro group-containing compounds and hardened polymer of the same Kyoeisha Chemical Co., Ltd. (JP) 2000-09-20 EP disclosed
JP-H07285925-A METHOD FOR PRODUCING METHYLENE-CROSS-LINKED TRIPHENYLENE TRIISOCYANATE MITSUI TOATSU CHEM INC 1995-10-31 JP disclosed