Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959904 | 1.00 | LMNA (0.62) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| SCHEMBL10957900 | 1.00 | LMNA (0.62) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| SCHEMBL10961357 | 1.00 | LMNA (0.62) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| SCHEMBL10959899 | 1.00 | LMNA (0.62) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL10957861 | 0.99 | LMNA (0.61) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL10957863 | 0.99 | LMNA (0.61) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL10957866 | 0.99 | LMNA (0.61) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| SCHEMBL10958937 | 0.86 | LMNA (0.66) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| SCHEMBL10956045 | 0.82 | LMNA (0.58) | LMNAHTR1AADRA1AKDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL10957802 | 0.81 | LMNA (0.57) | LMNAHTR1AADRA1AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072620-B1 | 3-METHYLFLAVONE-8-CARBOXYLIC ACID ESTERS | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1985-12-04 | — | — | EP | claimed |
| EP-0072620-A1 | 3-Methylflavone-8-carboxylic acid esters | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-02-23 | — | — | EP | claimed |