Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420289 | 0.87 | — | — | |
| SCHEMBL11420286 | 0.87 | — | — | |
| SCHEMBL11153114 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL11160918 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL11414378 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL19852932 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL11421254 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL11313291 | 0.86 | DGAT2 (0.37) | ASGR1 | |
| SCHEMBL8529076 | 0.83 | ASGR1 (0.30) | ASGR1 | |
| SCHEMBL10943549 | 0.81 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051280-B1 | ANTHRACYCLINE GLYCOSIDES, PROCESS FOR THE PREPARATION THEREOF, INTERMEDIATE COMPOUNDS AND THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | FARMITALIA CARLO ERBA S.p.A. (IT) | 1984-07-11 | — | — | EP | disclosed |
| US-4366149-A | LEUKEMIA TREATMENT | FARMITALIA CARLO ERBA S.R.L. | 1982-12-28 | — | — | US | disclosed |
| EP-0051280-A1 | Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions | FARMITALIA CARLO ERBA S.p.A. (IT) | 1982-05-12 | — | — | EP | disclosed |