Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039444 | 1.00 | TDP1 (0.40) | TDP1ALOX5APPCYP3A4ABCB1 | |
| SCHEMBL11037923 | 0.81 | CYP3A4 (0.55) | ALOX5APPCYP3A4TTRDPP4 | |
| SCHEMBL11144169 | 0.81 | CYP3A4 (0.55) | ALOX5APPCYP3A4TTRDPP4 | |
| SCHEMBL445162 | 0.74 | ATM (0.47) | TDP1CYP3A4 | |
| SCHEMBL11741179 | 0.74 | ATM (0.47) | TDP1CYP3A4 | |
| SCHEMBL445161 | 0.74 | ATM (0.47) | TDP1CYP3A4 | |
| SCHEMBL11145355 | 0.73 | THRA (0.40) | TDP1CYP3A4 | |
| SCHEMBL11138525 | 0.73 | TTR (0.50) | APPTTRCA12CA1CA2 | |
| SCHEMBL11138532 | 0.73 | TTR (0.50) | APPTTRCA12CA1CA2 | |
| SCHEMBL28327568 | 0.70 | ATM (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456668-A | DYE BLEACH, TEXTILE DYES | CIBA GEIGY AG (CH) | 1984-06-26 | — | — | US | disclosed |
| US-4409143-A | TEXTILES, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1983-10-11 | — | — | US | disclosed |