Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037201 | 0.92 | ALDH1A1 (0.49) | ALDH1A1ESR1TSHRKMT2AMEN1 | |
| SCHEMBL11038274 | 0.84 | EPHX1 (0.55) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL11039797 | 0.79 | ALDH1A1 (0.49) | ALDH1A1ESR1TSHRCHRM1SLC6A2 | |
| SCHEMBL8040937 | 0.78 | MEN1 (0.39) | ALDH1A1KMT2AMEN1HPGDEPHX1 | |
| SCHEMBL10949603 | 0.76 | ALDH1A1 (0.68) | ALDH1A1ESR1TSHRCHRM1SLC6A2 | |
| SCHEMBL6132117 | 0.74 | ALDH1A1 (0.57) | ALDH1A1ESR1TSHRCHRM1SLC6A2 | |
| SCHEMBL9488492 | 0.74 | MEN1 (0.45) | KMT2AMEN1POLBLMNAMAPT | |
| SCHEMBL11058213 | 0.74 | ALDH1A1 (0.53) | ALDH1A1ESR1TSHRCHRM1SLC6A2 | |
| SCHEMBL11058246 | 0.74 | ALDH1A1 (0.53) | ALDH1A1ESR1TSHRCHRM1SLC6A2 | |
| SCHEMBL10947673 | 0.73 | ALDH1A1 (0.64) | ALDH1A1ESR1TSHRCHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118046-A1 | Liquid crystal compounds, liquid crystal compositions and liquid crystal display devices | HITACHI, LTD. (JP) | 1984-09-12 | — | — | EP | disclosed |