Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038043 | 0.95 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11040173 | 0.86 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10794489 | 0.86 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11040626 | 0.84 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11431200 | 0.82 | ALDH1A1 (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28445117 | 0.81 | TSHR (0.61) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL11135065 | 0.80 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7535600 | 0.79 | TSHR (0.86) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL3190827 | 0.79 | TSHR (0.86) | TSHRNAAAPOLBAPEX1HTT | |
| SCHEMBL2060012 | 0.79 | TSHR (0.86) | TSHRNAAAPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446175-A | ACRYLATE, CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-01 | — | — | US | claimed |
| US-4436885-A | Preparation of isocyanate-functional polymers containing a terminal monosulfide group | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-13 | — | — | US | claimed |
| US-4351755-A | MOISTURE CURABLE COATINGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-28 | — | — | US | claimed |