Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039700 | 1.00 | HRH2 (0.35) | HRH2HRH4HRH3BCHEACHE | |
| Hydrochloric Acid SCHEMBL11075294 | 0.99 | HRH2 (0.35) | HRH2HRH4HRH3BCHEACHE | |
| SCHEMBL11091404 | 0.86 | BCHE (0.51) | HRH2HRH4HRH3BCHEACHE | |
| SCHEMBL11091406 | 0.86 | BCHE (0.51) | HRH2HRH4HRH3BCHEACHE | |
| Hydrochloric Acid SCHEMBL11081094 | 0.85 | ACHE (0.49) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL11041744 | 0.83 | ACHE (0.33) | BCHEACHE | |
| SCHEMBL7178167 | 0.82 | HRH4 (0.41) | HRH2HRH4HRH3EBPSIGMAR1 | |
| SCHEMBL9866042 | 0.79 | SCN5A (0.44) | HRH2HRH4HRH3EBPSIGMAR1 | |
| SCHEMBL11091410 | 0.79 | BCHE (0.51) | HRH2HRH4HRH3BCHEACHE | |
| SCHEMBL7175849 | 0.79 | HRH4 (0.36) | HRH2HRH4HRH3EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041359-B1 | PROCESS FOR THE PREPARATION OF HETEROCYCLYLALKYL GUANIDINES; INTERMEDIATES AND THEIR PREPARATION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-11-14 | — | — | EP | disclosed |