Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83312 | 0.97 | — | — | |
| SCHEMBL6018777 | 0.97 | ALOX15 (0.48) | ALOX15HSD17B10TET2TET3TET1 | |
| Ammonia Solution, Strong SCHEMBL1326303 | 0.94 | — | — | |
| Water SCHEMBL4964612 | 0.94 | — | — | |
| SCHEMBL28853784 | 0.94 | — | — | |
| Ethylene SCHEMBL27214133 | 0.94 | ALOX15 (0.46) | ALOX15HSD17B10TET2TET3TET1 | |
| Hydrochloric Acid SCHEMBL7552979 | 0.94 | — | — | |
| Acrylic Acid SCHEMBL18864325 | 0.90 | ALOX15 (0.60) | ALOX15HSD17B10TET2TET3TET1 | |
| Acrylic Acid SCHEMBL5610985 | 0.87 | ALOX15 (0.58) | ALOX15HSD17B10TET2TET3TET1 | |
| Methacrylic Acid SCHEMBL4557384 | 0.87 | ALOX15 (0.41) | ALOX15HSD17B10TET2TET3TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056526-B1 | CARBONATE(ALKYL)ACRYLATE RADIATION-CURABLE COATING COMPOSITIONS, AND METHOD OF CURING | MOBIL OIL CORPORATION (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0056526-A1 | Carbonate(alkyl)acrylate radiation-curable coating compositions, and method of curing | MOBIL OIL CORPORATION (US) | 1982-07-28 | — | — | EP | disclosed |