SCHEMBL11039730

SCHEMBL11039730

CC1CCCCC1(O)C#N

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24112695 0.93
SCHEMBL24477645 0.93
SCHEMBL927483 0.78 MAPT (0.33) ALDH1A1MAPT
SCHEMBL11178540 0.77 MAPT (0.33) ALDH1A1MAPT
SCHEMBL15363674 0.76 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ETSHR
SCHEMBL15048898 0.75 MAPT (0.32) MAPT
SCHEMBL15048939 0.75 MAPT (0.32) MAPT
SCHEMBL15049045 0.75 MAPT (0.32) MAPT
SCHEMBL15049281 0.75 MAPT (0.32) MAPT
SCHEMBL24450345 0.74 ALDH1A1 (0.35) ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178724-B Process for the preparation of compounds 四川大学 2020-09-11 CN claimed
WO-2021252644-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-12-16 WO disclosed
WO-2021212039-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-10-21 WO disclosed
CN-108178724-B Process for the preparation of compounds 四川大学 2020-09-11 CN disclosed
US-4482760-A HYDROGENATING A CYANOHYDRIN DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4070335-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4067848-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed