SCHEMBL11039835

SCHEMBL11039835

O=S(=O)(O)n1nc2ccccc2n1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 2/20 0.38
TDP1 Q9NUW8 2/20 0.36
APEX1 P27695 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.34
ACP1 P24666 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC9A1 P19634 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL28350810 0.86 EGLN3 (0.42) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL4015263 0.79 POLB (0.42) KDM4EHPGDL3MBTL1TSHRSMN1; SMN2
SCHEMBL4022733 0.76 POLB (0.40) KDM4EHPGDL3MBTL1TSHRPOLB
SCHEMBL24668984 0.75 KDM4E (0.41) KDM4EHPGDL3MBTL1TSHRSMN1; SMN2
SCHEMBL4021791 0.73 TSHR (0.41) KDM4EHPGDL3MBTL1TSHRPOLB
SCHEMBL4019898 0.72 ALDH1A1 (0.42) L3MBTL1TSHRPOLBCYP2C9CYP2C19
SCHEMBL11412223 0.71 KDM4E (0.38) KDM4EHPGDTSHRSMN1; SMN2TDP1
SCHEMBL4018744 0.71 ALDH1A1 (0.41) L3MBTL1TSHRPOLBCYP2C9CYP2C19
SCHEMBL4022186 0.71 ALDH1A1 (0.41) L3MBTL1TSHRPOLBCYP2C9CYP2C19
SCHEMBL4015858 0.71 ALDH1A1 (0.41) L3MBTL1TSHRPOLBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0112120-A2 Use of substituted 2-(2'-Hydroxyaryl)-2H-benzotriazolesulfonates as photostabilising agents for natural and synthetic fibres COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1984-06-27 EP claimed
WO-1984002365-A1 USE OF SUBSTITUTED 2-(2'-HYDROXYARYL)-2H-BENZOTRIAZOLESULFONATES AS PHOTOSTABILISING AGENTS FOR NATURAL AND SYNTHETIC FIBRES COMMW SCIENT IND RES ORG (AU) 1984-06-21 WO claimed