Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419410 | 0.83 | VKORC1 (0.49) | VKORC1TYRMEN1KMT2AADRA2C | |
| SCHEMBL11035649 | 0.75 | TYR (0.46) | VKORC1TYRMEN1KMT2ATSHR | |
| SCHEMBL9496068 | 0.74 | TYR (0.52) | VKORC1TYRMEN1KMT2ACYP2C9 | |
| SCHEMBL25266353 | 0.72 | TYR (0.50) | VKORC1TYRMEN1KMT2AADRA2C | |
| SCHEMBL661820 | 0.72 | TYR (0.50) | VKORC1TYRMEN1KMT2AADRA2C | |
| Hydrogen Peroxide SCHEMBL8846644 | 0.72 | ESR1 (0.55) | TYRMEN1KMT2ACYP2C9ADRA2C | |
| SCHEMBL9652788 | 0.72 | GPR35 (0.57) | VKORC1MEN1KMT2ACYP2C9CYP2D6 | |
| SCHEMBL5507568 | 0.72 | VKORC1 (0.41) | VKORC1TYRMEN1KMT2AHSD17B10 | |
| SCHEMBL9770025 | 0.72 | VKORC1 (0.41) | VKORC1TYRMEN1KMT2AADRA2C | |
| SCHEMBL10491803 | 0.72 | VKORC1 (0.41) | VKORC1TYRMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083428-B1 | PROCESS FOR PRODUCING BETA-NAPHTHOLS NOT SUBSTITUTED IN POSITION 1 AND SUBSTITUTED BY ARALIPHATIC GROUPS | BASF Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |