Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751588 | 0.92 | TSHR (0.52) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL11037937 | 0.86 | ALDH1A1 (0.47) | TSHRALDH1A1GLAMEN1KMT2A | |
| SCHEMBL6700583 | 0.86 | TSHR (0.46) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL29840012 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL30957339 | 0.80 | NPC1 (0.51) | ALDH1A1TP53 | |
| SCHEMBL5881190 | 0.79 | TSHR (0.50) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL7653267 | 0.79 | CYP3A4 (0.63) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL17078095 | 0.78 | TSHR (0.48) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL5512527 | 0.78 | ALDH1A1 (0.48) | TSHRALDH1A1GLALMNACYP3A4 | |
| SCHEMBL11064072 | 0.78 | TP53 (0.54) | TSHRALDH1A1GLALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | claimed |
| EP-0027330-B1 | PROCESS FOR THE PRODUCTION OF METHYLENEDICARBANILATES AND THE COMPOUNDS THUS OBTAINED | MITSUBISHI KASEI CORPORATION (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4476317-A | HETEROPOLYMOLYBDIC ACID OR HETEROPOLYTUNGSTIC ACID | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1984-10-09 | — | — | US | disclosed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | disclosed |