Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384030 | 0.80 | MAOB (0.57) | MAOBHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11040385 | 0.79 | HPGD (0.39) | HPGDHRH3MEN1KMT2AMAPT | |
| SCHEMBL10984547 | 0.79 | ABCB1 (0.41) | ABCB1MAOBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10986476 | 0.79 | S1PR1 (0.48) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11043402 | 0.78 | TSHR (0.43) | ABCB1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6448598 | 0.78 | SMN1; SMN2 (0.56) | MAOBHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5530918 | 0.77 | MEN1 (0.53) | MAOBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL23173884 | 0.77 | MAOB (0.53) | MAOBHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22918087 | 0.77 | MAOB (0.53) | MAOBMEN1KMT2ALRRK2SMN1; SMN2 | |
| SCHEMBL29660966 | 0.77 | MAOB (0.53) | MAOBMEN1KMT2ALRRK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |