Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040306 | 0.79 | ABCB1 (0.46) | HPGDMEN1KMT2AHRH3L3MBTL1 | |
| SCHEMBL11040290 | 0.77 | KDM4E (0.40) | HPGDMEN1KMT2AALDH1A3MAPK1 | |
| SCHEMBL27833449 | 0.71 | TDP1 (0.50) | HTR1AL3MBTL1MAPK1LMNAADRA1A | |
| SCHEMBL28332609 | 0.69 | MRGPRX4 (0.44) | HTR1AL3MBTL1MAPK1LMNAADRA1A | |
| SCHEMBL9047388 | 0.69 | HTR1A (0.72) | HPGDHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17659018 | 0.69 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL6201707 | 0.69 | HTR1A (0.49) | HPGDHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11219312 | 0.69 | ALDH1A3 (0.54) | HPGDMEN1KMT2AALDH1A3MAPK1 | |
| SCHEMBL25539406 | 0.68 | HTR1A (0.48) | HPGDHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16046661 | 0.68 | HTR1A (0.74) | HPGDHTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |