Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940732 | 0.90 | KMT2A (0.55) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL10943737 | 0.85 | HPGD (0.49) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL1929497 | 0.73 | KDM4E (0.44) | KDM4EMAPTKMT2APOLBALDH1A1 | |
| SCHEMBL2350891 | 0.72 | KDM4E (0.54) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL10369208 | 0.71 | KDM4E (0.50) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL11008658 | 0.71 | ALDH1A1 (0.62) | KDM4EMAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL68410 | 0.70 | SMN1; SMN2 (0.71) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL7470961 | 0.68 | PDE4D (0.65) | KDM4EMAPTKMT2APOLBHPGD | |
| SCHEMBL522227 | 0.68 | ESR1 (0.55) | KDM4EMAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29202767 | 0.67 | HPGD (0.56) | KDM4EMAPTKMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461642-A | 2,5-BIS(PERFLUOROALKYL)-3,4-PYRROLEDICARBOXYLATES | MONSANTO COMPANY (US) | 1984-07-24 | — | — | US | disclosed |