Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 4/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035995 | 0.96 | MCHR1 (0.65) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11041348 | 0.92 | SRC (0.58) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11041327 | 0.91 | SRC (0.57) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11037545 | 0.87 | NCF1 (0.65) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11037639 | 0.87 | NCF1 (0.61) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11036820 | 0.87 | NCF1 (0.61) | MCHR1SRCSOS2NCF1PLAU | |
| SCHEMBL11039714 | 0.86 | NCF1 (0.64) | MCHR1SRCSOS2NCF1KDM4E | |
| SCHEMBL11035896 | 0.82 | MCHR1 (0.47) | MCHR1SRCSOS2NCF1KDM4E | |
| SCHEMBL10063304 | 0.81 | MCHR1 (0.72) | MCHR1NCF1KDM4EMAPTLMNA | |
| SCHEMBL10063463 | 0.80 | MCHR1 (0.70) | MCHR1NCF1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125276-A1 | NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HÖGBERG, Sverker (SE) | 1984-11-21 | — | — | EP | disclosed |
| WO-1984001946-A1 | NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HOEGBERG SVERKER | 1984-05-24 | — | — | WO | disclosed |