Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.74 |
| ▸ | CA1 | P00915 | 17/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL31095056 | 0.97 | CA2 (0.78) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL104073 | 0.97 | CA2 (0.78) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL15641843 | 0.93 | CA2 (0.74) | CA2CA1CA4MAPT | |
| Terephthalic Acid SCHEMBL15124721 | 0.93 | CA2 (0.74) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL7897885 | 0.93 | CA2 (0.74) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL9930111 | 0.93 | CA2 (0.74) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28774454 | 0.90 | CA2 (0.70) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL6665082 | 0.90 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL10900872 | 0.90 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL166041 | 0.90 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457814-A | TO P-HYDROXYMETHYLBENZOIC ACID | STANDARD OIL COMPANY (INDIANA) (US) | 1984-07-03 | — | — | US | disclosed |