Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675175 | 0.92 | ELANE (0.68) | ELANEMAPTKMT2APRSS1ACR | |
| SCHEMBL11038727 | 0.83 | ELANE (0.53) | ELANEMAPTKMT2APRSS1ACR | |
| SCHEMBL11039303 | 0.83 | PARP10 (0.60) | ELANEMAPTKMT2AGLATSHR | |
| SCHEMBL27831314 | 0.79 | ELANE (0.75) | ELANEMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11036708 | 0.79 | CA12 (0.50) | ELANEMAPTKMT2ATSHRMEN1 | |
| SCHEMBL11036788 | 0.79 | ELANE (0.58) | ELANEMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12141774 | 0.78 | MAPT (0.64) | MAPTKMT2APRSS1GLATSHR | |
| SCHEMBL12616904 | 0.77 | ELANE (0.70) | ELANEMAPTKMT2APRSS1ACR | |
| SCHEMBL21795326 | 0.76 | ELANE (0.79) | ELANEMAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL20279324 | 0.75 | ELANE (0.54) | ELANEMAPTKMT2APRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046144-B1 | THERAPEUTICALLY ACTIVE DERIVATIVES OF PHENYLETHANOL AMINES | Aktiebolaget Draco (SE) | 1984-04-11 | — | — | EP | disclosed |
| US-4442300-A | BRONCHOSPASMOLYTIC | AKTIEBOLAGET DRACO (SE) | 1984-04-10 | — | — | US | disclosed |
| EP-0046144-A1 | Therapeutically active derivatives of phenylethanol amines | Aktiebolaget Draco (SE) | 1982-02-17 | — | — | EP | disclosed |