Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336605 | 0.84 | ELANE (0.75) | ELANEMAPTL3MBTL1PRTN3 | |
| SCHEMBL11037438 | 0.83 | ELANE (0.53) | ELANEMAPTTDP1L3MBTL1PRTN3 | |
| SCHEMBL11039303 | 0.83 | PARP10 (0.60) | ELANEMAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL11036708 | 0.82 | CA12 (0.50) | ELANEMAPTTDP1KMT2AMEN1 | |
| SCHEMBL16300513 | 0.81 | ELANE (0.73) | ELANEMAPTTDP1L3MBTL1PRTN3 | |
| SCHEMBL19335219 | 0.79 | CA5A (0.55) | ELANE | |
| SCHEMBL11040475 | 0.79 | ELANE (0.58) | ELANEMAPTTDP1KMT2AMEN1 | |
| SCHEMBL12141774 | 0.78 | MAPT (0.64) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL11040246 | 0.77 | ELANE (0.50) | ELANEMAPTTDP1L3MBTL1PRTN3 | |
| SCHEMBL17585016 | 0.77 | ELANE (0.70) | ELANEMAPTTDP1PRTN3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046144-B1 | THERAPEUTICALLY ACTIVE DERIVATIVES OF PHENYLETHANOL AMINES | Aktiebolaget Draco (SE) | 1984-04-11 | — | — | EP | disclosed |
| US-4442300-A | BRONCHOSPASMOLYTIC | AKTIEBOLAGET DRACO (SE) | 1984-04-10 | — | — | US | disclosed |
| EP-0046144-A1 | Therapeutically active derivatives of phenylethanol amines | Aktiebolaget Draco (SE) | 1982-02-17 | — | — | EP | disclosed |