Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036091 | 1.00 | TSHR (0.49) | TSHRALDH1A1GAAHSD17B10KMT2A | |
| SCHEMBL8938798 | 0.91 | TSHR (0.58) | TSHRALDH1A1GAAHSD17B10KMT2A | |
| Threonine SCHEMBL562233 | 0.77 | HTR2A (0.42) | ALDH1A1KMT2ASLC1A2LMNAMEN1 | |
| Threonine SCHEMBL10663811 | 0.77 | HTR2A (0.42) | ALDH1A1KMT2ASLC1A2LMNAMEN1 | |
| Threonine SCHEMBL567434 | 0.77 | HTR2A (0.42) | ALDH1A1KMT2ASLC1A2LMNAMEN1 | |
| SCHEMBL7059170 | 0.76 | CYP2D6 (0.38) | KMT2ASLC1A2MEN1CYP1A2CYP2C9 | |
| SCHEMBL9841927 | 0.76 | CYP2D6 (0.38) | KMT2ASLC1A2MEN1CYP1A2CYP2C9 | |
| SCHEMBL28896711 | 0.76 | SLC1A2 (0.38) | KMT2ASLC1A2MEN1CYP1A2CYP2C9 | |
| SCHEMBL10517046 | 0.74 | TSHR (0.63) | TSHRALDH1A1GAAHSD17B10KMT2A | |
| SCHEMBL6425252 | 0.73 | TSHR (0.61) | TSHRALDH1A1GAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |