Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041077 | 0.78 | KMT2A (0.50) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL11253382 | 0.77 | KMT2A (0.43) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL31619090 | 0.74 | KMT2A (0.41) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL28211469 | 0.74 | KMT2A (0.41) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL504737 | 0.73 | KMT2A (0.40) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL12611006 | 0.71 | KMT2A (0.44) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL30117303 | 0.71 | TDP1 (0.56) | TDP1L3MBTL1TP53ESR1POLB | |
| Acrylic Acid SCHEMBL10706068 | 0.70 | KMT2A (0.38) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL28971471 | 0.70 | KMT2A (0.38) | TDP1L3MBTL1TP53ESR1POLB | |
| SCHEMBL8144185 | 0.70 | ALDH1A1 (0.35) | TP53POLBMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040889-B1 | ACTIVATORS FOR ZIEGLER TYPE POLYMERIZATION CATALYSTS | UNIROYAL, INC. (US) | 1984-05-30 | — | — | EP | claimed |
| US-4347159-A | CHLORINATED ESTER OF (TETRAHYDRO)FUROIC ACID | UNIROYAL, INC. (US) | 1982-08-31 | — | — | US | claimed |
| EP-0040889-B1 | ACTIVATORS FOR ZIEGLER TYPE POLYMERIZATION CATALYSTS | UNIROYAL, INC. (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4451575-A | Activators for Ziegler type polymerization catalysts using bis(trichloromethyl) sulfone | UNIROYAL, INC. (US) | 1984-05-29 | — | — | US | disclosed |