SCHEMBL11040911

SCHEMBL11040911

COc1ccc2c3c(ccc(OC)c13)C(=O)N(C)C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.67
KMT2A Q03164 7/20 0.47
ALDH1A1 P00352 5/20 0.47
POLB P06746 4/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 1/20 0.47
PABPC1 P11940 1/20 0.47
XBP1 P17861 1/20 0.47
NFKB1 P19838 1/20 0.47
HTT P42858 1/20 0.47
SMARCA2 P51531 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
CYP19A1 P11511 2/20 0.47
NQO2 P16083 2/20 0.47
MEN1 O00255 6/20 0.43
USP2 O75604 3/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2633374 0.89 PRMT1 (0.59) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL20735045 0.85 PRMT1 (0.59) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL127059 0.82 MEN1 (0.55) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL30937815 0.82 MEN1 (0.55) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL20734988 0.82 PRMT1 (0.49) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL20734987 0.82 PRMT1 (0.49) PRMT1MAPTAPP
SCHEMBL20735081 0.81 RAB9A (0.56) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL30487872 0.80 PRMT1 (1.00) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL438891 0.80 PRMT1 (1.00) PRMT1KMT2AALDH1A1POLBKDM4E
SCHEMBL11499812 0.80 TOP2A (0.49) PRMT1KMT2AALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0033018-B1 MIXTURES OF OPTICAL BRIGHTENERS BASF Aktiengesellschaft (DE) 1985-04-10 EP disclosed
EP-0029972-B1 PREPARATION FOR BRIGHTENING SYNTHETIC FIBRES, PROCESS FOR ITS PREPARATION AND PROCESS FOR OPTICAL BRIGHTENING CASSELLA Aktiengesellschaft (DE) 1984-09-19 EP disclosed
EP-0044995-A1 Dispersion of brightening agents containing graft polymers CASSELLA Aktiengesellschaft (DE) 1982-02-03 EP disclosed
US-4304569-A Formulation for brightening synthetic fibers and its preparation and use CASSELLA AG. (DE) 1981-12-08 US disclosed
EP-0029972-A2 Preparation for brightening synthetic fibres, process for its preparation and process for optical brightening CASSELLA Aktiengesellschaft (DE) 1981-06-10 EP disclosed