Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652666 | 0.85 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4864448 | 0.82 | TDP1 (0.57) | TDP1TSHRMAPK1SMN1; SMN2VCAM1 | |
| SCHEMBL9516342 | 0.80 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL1265167 | 0.80 | TDP1 (0.54) | TDP1GPR35TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL278506 | 0.80 | TDP1 (0.67) | TDP1TSHRMAPK1SMN1; SMN2VCAM1 | |
| SCHEMBL2651124 | 0.80 | TDP1 (0.54) | TDP1GPR35TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL30256667 | 0.80 | TDP1 (0.67) | TDP1TSHRMAPK1SMN1; SMN2VCAM1 | |
| SCHEMBL28755195 | 0.78 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL2002527 | 0.78 | TDP1 (0.53) | TDP1TSHRMAPK1SMN1; SMN2VCAM1 | |
| SCHEMBL4011818 | 0.77 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039030-B1 | COUPLER COMPONENTS FOR OXIDATIVE HAIR DYES, THEIR PREPARATION AND THEIR USE, AND HAIR DYEING COMPOSITIONS CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0039030-A1 | Coupler components for oxidative hair dyes, their preparation and their use, and hair dyeing compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-11-04 | — | — | EP | disclosed |