Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4217608 | 0.83 | TDP1 (0.55) | TDP1GPR35TSHRMAPK1ALDH1A1 | |
| SCHEMBL31170798 | 0.83 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL5595026 | 0.83 | TDP1 (0.67) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL278488 | 0.80 | TDP1 (1.00) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL10485141 | 0.80 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1ALDH1A1 | |
| SCHEMBL34473568 | 0.80 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL4011818 | 0.80 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL29244091 | 0.80 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1ALDH1A1 | |
| SCHEMBL11040922 | 0.80 | TDP1 (0.52) | TDP1GPR35TSHRMAPK1VCAM1 | |
| SCHEMBL28391943 | 0.79 | TDP1 (0.81) | TDP1GPR35TSHRMAPK1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155823-A | — | — | None | — | — | JP | disclosed |
| JP-H05155823-A | PURIFICATION OF 2,6-DICHLORO-4-NITROANILINE | MITSUI TOATSU CHEM INC | 1993-06-22 | — | — | JP | disclosed |