Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | MMP16 | P51512 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049312 | 0.94 | SMN1; SMN2 (0.53) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11042608 | 0.91 | GAA (0.56) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11122778 | 0.90 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11124125 | 0.89 | GAA (0.58) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11042573 | 0.88 | MAPT (0.49) | GAAMAPTTP53MMP2MMP8 | |
| SCHEMBL11047175 | 0.88 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10646472 | 0.88 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11046520 | 0.87 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10616134 | 0.87 | GAA (0.67) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11049002 | 0.87 | GAA (0.56) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348219-A | PREEMERGENCE AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4454335-A | Substituted benzene sulfonyl isocyanates as intermediates to herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4348219-A | PREEMERGENCE AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| US-4348219-A | PREEMERGENCE AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |