Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP12 | P39900 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 4/20 | 0.46 |
| ▸ | MMP16 | P51512 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040338 | 0.94 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1MMP2 | |
| SCHEMBL11124612 | 0.88 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL11041299 | 0.88 | GAA (0.56) | MAPTALDH1A1KDM4ENPC1MMP2 | |
| SCHEMBL10644690 | 0.87 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL11044864 | 0.87 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL11052432 | 0.85 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ENPC1GAA | |
| SCHEMBL11043191 | 0.85 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ENPC1MMP2 | |
| SCHEMBL11095782 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ENPC1MMP2 | |
| SCHEMBL11049312 | 0.84 | SMN1; SMN2 (0.53) | MAPTMMP2MMP8MMP12MMP13 | |
| SCHEMBL10683450 | 0.84 | MMP2 (0.42) | MAPTALDH1A1KDM4ENPC1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348219-A | PREEMERGENCE AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4454335-A | Substituted benzene sulfonyl isocyanates as intermediates to herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4348219-A | PREEMERGENCE AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |