Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10766647 | 0.92 | LMNA (0.52) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL3331291 | 0.84 | LMNA (0.52) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL28359008 | 0.78 | LMNA (0.53) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL10741295 | 0.78 | POLB (0.56) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL569823 | 0.77 | LMNA (0.48) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL675157 | 0.75 | LMNA (0.58) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL10766642 | 0.75 | LMNA (0.51) | LMNAPKMNPSR1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11040640 | 0.75 | LMNA (0.47) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL435089 | 0.74 | LMNA (0.49) | LMNAPKMNPSR1ALDH1A1MAPT | |
| SCHEMBL11039178 | 0.74 | LMNA (0.47) | LMNAPKMNPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048040-B1 | 7-SUBSTITUTED 2,3-DIHYDROBENZOFURANS, THEIR PREPARATION AND THEIR USE AS PESTICIDES OR AS CHEMICAL INTERMEDIATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-08-29 | — | — | EP | disclosed |
| US-4467104-A | Esters of 2-(2-chlorocarbonyl)-2-(2,3-dihydro-2-alkylbenzofuran-7-yl)-hydrazinecarboxylic acid | SHELL OIL COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4406910-A | INSECTICIDES, MITICIDES | SHELL OIL COMPANY (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0048040-A1 | 7-Substituted 2,3-dihydrobenzofurans, their preparation and their use as pesticides or as chemical intermediates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-03-24 | — | — | EP | disclosed |