SCHEMBL11041422

SCHEMBL11041422

CCC(C=C(Cl)Cl)(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085821 0.73
SCHEMBL11047184 0.71
Trichloroethylene SCHEMBL10417609 0.69 TSHR (0.50) TSHRTDP1CASP1
SCHEMBL15743080 0.62
Trichloroethylene SCHEMBL6743892 0.62
SCHEMBL3055197 0.62
SCHEMBL11046442 0.61
Hypochlorous Acid SCHEMBL11410754 0.60
Trichloroethylene SCHEMBL1356814 0.60 TSHR (0.57) TSHRTDP1CASP1
SCHEMBL5575210 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460793-A REACTING 1,1-DICHLOROALKENE AND PHENOLATE TO OBTAIN PHENYLETHER INTERMEDIATE, ACID HYDROLYSIS BAYER AKTIENGESELLSCHAFT (DE) 1984-07-17 US disclosed
EP-0055427-B1 PROCESS FOR THE PRODUCTION OF MONOCHLOROMETHYL KETONES BAYER AG (DE) 1984-05-02 EP disclosed
EP-0055427-A1 Process for the production of monochloromethyl ketones BAYER AG (DE) 1982-07-07 EP disclosed