⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113744 | 0.81 | — | — | |
| SCHEMBL5157729 | 0.67 | — | — | |
| SCHEMBL3051104 | 0.67 | — | — | |
| SCHEMBL3049765 | 0.67 | — | — | |
| SCHEMBL16932027 | 0.67 | — | — | |
| SCHEMBL15163204 | 0.67 | — | — | |
| SCHEMBL9668834 | 0.65 | — | — | |
| SCHEMBL270569 | 0.65 | — | — | |
| SCHEMBL11041422 | 0.62 | TSHR (0.33) | — | |
| SCHEMBL2768911 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718611-B2 | Cyclic nonapeptide amides | AICURIS GMBH & CO. KG (DE) | 2010-05-18 | — | — | US | claimed |
| EP-1809654-B1 | HETEROCYCLYL-SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2008-10-08 | — | — | EP | claimed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | claimed |
| US-20080051424-A1 | Heterocyclyl-substituted nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-02-28 | — | — | US | claimed |
| US-7718611-B2 | Cyclic nonapeptide amides | AICURIS GMBH & CO. KG (DE) | 2010-05-18 | — | — | US | disclosed |
| EP-1809654-B1 | HETEROCYCLYL-SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080051424-A1 | Heterocyclyl-substituted nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-02-28 | — | — | US | disclosed |
| EP-1809654-A1 | HETEROCYCLYL-SUBSTITUTED NONADEPSIPEPTIDES | AiCuris GmbH & Co. KG (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006042653-A1 | HETEROCYCLYL-SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO. KG (DE) | 2006-04-27 | — | — | WO | disclosed |