Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065252 | 0.95 | TSHR (0.77) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL28492787 | 0.94 | TSHR (0.74) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL9420542 | 0.92 | ALDH1A1 (0.73) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL5599951 | 0.89 | TSHR (0.89) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL2809758 | 0.89 | TSHR (0.89) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL1805376 | 0.87 | ALDH1A1 (0.80) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| Hydroquinone SCHEMBL9448724 | 0.86 | ALDH1A1 (0.65) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL11069187 | 0.86 | ALDH1A1 (0.73) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL9078373 | 0.84 | TSHR (0.65) | TSHRALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL8900471 | 0.84 | TSHR (0.80) | TSHRALDH1A1HSD17B10TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321033-B | Preparation method of tarceva | JIANGSU HUIFENG AGROCHEMICAL CO LTD | 2013-10-09 | — | — | CN | claimed |
| CN-102321033-B | Preparation method of tarceva | JIANGSU HUIFENG AGROCHEMICAL CO LTD | 2013-10-09 | — | — | CN | disclosed |
| CN-103070868-A | IDO inhibitor containing NH-1,2,3-triazole and preparation method thereof | UNIV FUDAN | 2013-05-01 | — | — | CN | disclosed |
| US-4456668-A | DYE BLEACH, TEXTILE DYES | CIBA GEIGY AG (CH) | 1984-06-26 | — | — | US | disclosed |
| US-4409143-A | TEXTILES, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1983-10-11 | — | — | US | disclosed |