Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11341018 | 0.86 | ALDH1A1 (0.33) | — | |
| SCHEMBL16673531 | 0.82 | — | — | |
| SCHEMBL19226217 | 0.82 | — | — | |
| Thiophene SCHEMBL29064509 | 0.77 | — | — | |
| SCHEMBL24477589 | 0.77 | CA1 (0.31) | — | |
| SCHEMBL9731404 | 0.77 | — | — | |
| SCHEMBL12166751 | 0.77 | CA1 (0.31) | — | |
| SCHEMBL13520346 | 0.72 | — | — | |
| SCHEMBL19240891 | 0.72 | — | — | |
| SCHEMBL5150110 | 0.71 | ALDH1A1 (0.34) | CYP2C9TSHRCYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034876-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4287212-A | USEFUL AS ANALGESICS AND DIURETICS | AMERICAN HOECHST CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |