Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558 | 0.97 | — | — | |
| SCHEMBL11014727 | 0.94 | — | — | |
| Ammonia Solution, Strong SCHEMBL27974201 | 0.94 | — | — | |
| SCHEMBL7229497 | 0.80 | TSHR (0.35) | TSHRLMNAMAPTSMN1; SMN2TDP1 | |
| SCHEMBL7237664 | 0.80 | TSHR (0.35) | TSHRLMNAMAPTSMN1; SMN2TDP1 | |
| SCHEMBL4812651 | 0.78 | — | — | |
| SCHEMBL11133563 | 0.77 | LMNA (0.42) | TSHRLMNACYP2D6MAPTALDH1A1 | |
| SCHEMBL72471 | 0.77 | LMNA (0.62) | TSHRLMNACYP2D6MAPTALDH1A1 | |
| SCHEMBL229792 | 0.77 | TSHR (0.50) | TSHRLMNACYP2D6MAPTALDH1A1 | |
| SCHEMBL1591285 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436640-A | OIL ADDITIVES; EXTREME PRESSURE LUBRICANTS | CHEVRON RESEARCH COMPANY (US) | 1984-03-13 | — | — | US | disclosed |