Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | SELL | P14151 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SELP | P16109 | 1/20 | 0.59 |
| ▸ | FUT4 | P22083 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139 | 0.78 | KDM4E (0.59) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL8731833 | 0.77 | TTR (0.61) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL352369 | 0.77 | KDM4E (0.65) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Gallic Acid SCHEMBL5421738 | 0.76 | CA12 (0.90) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Gallic Acid SCHEMBL28279123 | 0.76 | CA12 (0.90) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Water SCHEMBL1637239 | 0.76 | KDM4E (0.56) | KDM4ELMNATDP1ALDH1A1MAPT | |
| SCHEMBL407763 | 0.74 | KDM4E (0.62) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Gallic Acid SCHEMBL8088102 | 0.74 | CA12 (1.00) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Gallic Acid SCHEMBL1845406 | 0.74 | CA12 (1.00) | KDM4ELMNATDP1ALDH1A1MAPT | |
| Gallic Acid SCHEMBL678990 | 0.74 | CA12 (1.00) | KDM4ELMNATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |