Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594621 | 0.95 | HTT (0.62) | HTTALDH1A1HSP90AA1CA2CA9 | |
| SCHEMBL28087812 | 0.93 | HTT (0.60) | HTTALDH1A1HSP90AA1CA2CA9 | |
| Iodobenzene SCHEMBL2904039 | 0.88 | MEN1 (0.55) | HTTALDH1A1HSP90AA1CA2CA9 | |
| SCHEMBL11538154 | 0.86 | GPR17 (0.51) | HTTALDH1A1HSP90AA1CA2CA9 | |
| SCHEMBL31672153 | 0.86 | GPR17 (0.51) | HTTALDH1A1HSP90AA1CA2CA9 | |
| SCHEMBL927603 | 0.85 | ALDH1A1 (0.57) | HTTALDH1A1HSP90AA1CA2CA9 | |
| SCHEMBL28326326 | 0.84 | HTT (0.66) | HTTALDH1A1CA2CA9CA1 | |
| SCHEMBL7335028 | 0.83 | GPR17 (0.69) | HTTCA2LMNAMEN1MAPT | |
| SCHEMBL27464615 | 0.83 | KMT2A (0.60) | HTTCA2CA1LMNAMEN1 | |
| SCHEMBL2234824 | 0.83 | HSP90AA1 (0.63) | HTTALDH1A1HSP90AA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186028-A | Thiadiazole amide compound containing sulfonate structure, and preparation method and application thereof | 贵州大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-100516034-C | Aspartyl protease inhibitors | VERTEX PHARMA CO LTD (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101245058-A | Inhibitors of aspartyl protease | VERTEX PHARMA (US) | 2008-08-20 | — | — | CN | disclosed |
| CN-100339766-C | Preparations of carbon nano tube layout film or composite material from polymerisable semgental surface modified carbon nano tubes | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-09-26 | — | — | CN | disclosed |
| CN-1530404-A | Preparations of carbon nano tube layout film or composite material from polymerisable semgental surface modified carbon nano tubes | ���ǵ�����ʽ���� | 2004-09-22 | — | — | CN | disclosed |
| CN-1361765-A | Aspartyl protease inhibitors | VERTEX PHARMA (US) | 2002-07-31 | — | — | CN | disclosed |
| US-4433156-A | Process for preparing fluoran derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| US-4172089-A | COMPLEMENT INHIBITOR TRI- OR HEXA-PHENYL ESTER INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4117003-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-09-26 | — | — | US | disclosed |