Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949603 | 0.95 | ALDH1A1 (0.68) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL28881217 | 0.89 | ALDH1A1 (0.75) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL11041290 | 0.89 | RARB (0.65) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL19737251 | 0.88 | CA12 (0.58) | ALDH1A1ESR1LMNASMN1; SMN2MAPT | |
| SCHEMBL11037097 | 0.88 | RARB (0.66) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL11038862 | 0.88 | RARB (0.66) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL17742319 | 0.88 | MAPT (0.64) | TSHRALDH1A1ESR1LMNASMN1; SMN2 | |
| SCHEMBL24793774 | 0.85 | TSHR (0.54) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL10947673 | 0.85 | ALDH1A1 (0.64) | TSHRALDH1A1ESR1CHRM1SLC6A2 | |
| SCHEMBL10950553 | 0.85 | ESR1 (0.70) | TSHRALDH1A1ESR1CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118046-A1 | Liquid crystal compounds, liquid crystal compositions and liquid crystal display devices | HITACHI, LTD. (JP) | 1984-09-12 | — | — | EP | disclosed |