Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045668 | 0.81 | ACHE (0.42) | ACHEKMT2AKDM4EMEN1POLB | |
| SCHEMBL6197131 | 0.78 | GSK3B (0.47) | GSK3BKMT2AKDM4EMEN1MAPT | |
| SCHEMBL28016020 | 0.78 | KMT2A (0.49) | ACHEKMT2AKDM4EMEN1POLB | |
| SCHEMBL5050018 | 0.74 | GSK3B (0.47) | GSK3BKMT2AKDM4EMEN1L3MBTL1 | |
| SCHEMBL11473797 | 0.74 | ACHE (0.43) | ACHEKMT2AKDM4EMEN1POLB | |
| SCHEMBL11105265 | 0.73 | ELANE (0.47) | GSK3BPTPN1 | |
| Cyclopentane SCHEMBL11108749 | 0.73 | GSK3B (0.43) | GSK3BKMT2AKDM4EMEN1POLB | |
| SCHEMBL333513 | 0.73 | GSK3B (0.66) | GSK3BKMT2AKDM4EPOLBGAA | |
| SCHEMBL28067899 | 0.73 | CYP4F2 (0.45) | ACHEKMT2AKDM4EMEN1POLB | |
| SCHEMBL28644582 | 0.71 | ACHE (0.45) | ACHEKMT2AKDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043807-B1 | 1-(DIHYDROXYPHENYL)-2-AMINO-ETHANOL DERIVATIVES; PREPARATION, COMPOSITIONS AND INTERMEDIATES | Aktiebolaget Draco (SE) | 1984-05-30 | — | — | EP | disclosed |
| US-4451663-A | TERBUTALINE DERIVATIVES OF LONG DURATION AN REDUCED SIDE EFFECTS | AKTIEBOLAGET DRACO (SE) | 1984-05-29 | — | — | US | disclosed |
| US-4419364-A | Bronchospasmolytic carbamate derivatives | AKTIEBOLAGET DRACO (SE) | 1983-12-06 | — | — | US | disclosed |
| EP-0043807-A2 | 1-(Dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates | Aktiebolaget Draco (SE) | 1982-01-13 | — | — | EP | disclosed |