Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671615 | 0.84 | HTT (0.54) | HTTFGFR1 | |
| SCHEMBL157265 | 0.83 | HTT (1.00) | HTTFGFR1 | |
| Benzene SCHEMBL14876970 | 0.83 | HTT (1.00) | HTTFGFR1 | |
| Iodide SCHEMBL30645138 | 0.82 | HTT (0.96) | HTTFGFR1 | |
| SCHEMBL467858 | 0.82 | HTT (0.96) | HTTFGFR1 | |
| SCHEMBL4891428 | 0.82 | HTT (0.96) | HTTFGFR1 | |
| SCHEMBL27724758 | 0.82 | HTT (0.96) | HTTFGFR1 | |
| SCHEMBL30402227 | 0.78 | HTT (0.88) | HTTFGFR1ALDH1A1 | |
| SCHEMBL3419279 | 0.78 | HTT (0.88) | HTTFGFR1ALDH1A1 | |
| Benzimidazole SCHEMBL1347288 | 0.78 | KDM4E (0.50) | HTTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542394-A | MULTILAYER-DIAZONIUM LAYER AND COUPLER LAYER CONTAINING BENZIMIDAZOLE COMPOUND | RICOH COMPANY, LTD. (JP) | 1985-09-17 | — | — | US | disclosed |