Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038443 | 1.00 | NCF1 (0.60) | NCF1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL11037035 | 1.00 | NCF1 (0.60) | NCF1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL11037627 | 0.93 | NCF1 (0.62) | NCF1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL11040523 | 0.91 | KMT2A (0.57) | NCF1KDM4EKMT2ALMNARAB9A | |
| SCHEMBL11037636 | 0.91 | KDM4E (0.57) | NCF1KDM4EKMT2AMAPTLMNA | |
| SCHEMBL11035922 | 0.90 | KDM4E (0.55) | NCF1KDM4EKMT2ALMNAMMP2 | |
| SCHEMBL11041376 | 0.90 | KDM4E (0.55) | NCF1KDM4EKMT2ALMNAMMP2 | |
| SCHEMBL1000827 | 0.83 | MCHR1 (0.64) | NCF1KDM4EKMT2AMAPTLMNA | |
| SCHEMBL11038409 | 0.83 | MCHR1 (0.64) | NCF1KDM4EKMT2AMAPTLMNA | |
| SCHEMBL11036835 | 0.83 | MCHR1 (0.64) | NCF1KDM4EKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125276-A1 | NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HÖGBERG, Sverker (SE) | 1984-11-21 | — | — | EP | disclosed |
| WO-1984001946-A1 | NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HOEGBERG SVERKER | 1984-05-24 | — | — | WO | disclosed |