Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 6/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016386 | 1.00 | REN (0.43) | RENCTSLCTSBCTSSMMP2 | |
| SCHEMBL11015814 | 1.00 | REN (0.43) | RENCTSLCTSBCTSSMMP2 | |
| SCHEMBL11015310 | 0.90 | REN (0.53) | RENCTSLCTSBCTSSCASP3 | |
| SCHEMBL11015890 | 0.90 | REN (0.53) | RENCTSLCTSBCTSSCASP3 | |
| SCHEMBL11014291 | 0.90 | REN (0.53) | RENCTSLCTSBCTSSCASP3 | |
| SCHEMBL10721020 | 0.83 | REN (0.44) | RENCTSLCTSBCTSSMMP2 | |
| SCHEMBL10721167 | 0.83 | REN (0.44) | RENCTSLCTSBCTSSMMP2 | |
| SCHEMBL10721157 | 0.83 | REN (0.44) | RENMMP2MMP9MMP8HDAC1 | |
| SCHEMBL10721016 | 0.83 | REN (0.44) | RENMMP2MMP9MMP8HDAC1 | |
| SCHEMBL10725225 | 0.82 | REN (0.43) | RENCTSBMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |