Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893739 | 0.86 | PPARG (0.50) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL6136976 | 0.85 | PPARG (0.57) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL9733285 | 0.83 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL10894773 | 0.82 | PPARG (0.51) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| Acetic Acid Methyl Ester SCHEMBL10558983 | 0.82 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| Acetic Acid Methyl Ester SCHEMBL10559846 | 0.82 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL9734175 | 0.81 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL9734709 | 0.81 | PPARG (0.47) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL9734553 | 0.81 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1MAPTMEN1PDE5A | |
| SCHEMBL6138926 | 0.80 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1MAPTMEN1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106565-A1 | Leukotriene antagonists, their production, and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-04-25 | — | — | EP | disclosed |