Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733472 | 0.82 | CES2 (0.63) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL728756 | 0.80 | CES2 (0.61) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL29904845 | 0.79 | CES2 (0.54) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11199460 | 0.78 | KDM4E (0.64) | CES2CES1HPGDALDH1A1MEN1 | |
| SCHEMBL5676868 | 0.77 | CES2 (0.52) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| Beta-Naphtoic Acid SCHEMBL25370444 | 0.77 | CES2 (0.68) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| Beta-Naphtoic Acid SCHEMBL27548013 | 0.77 | CES2 (0.68) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11946959 | 0.77 | PTPN1 (0.57) | CES2CES1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10933256 | 0.76 | ATM (0.46) | CES2CES1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7220072 | 0.76 | CES2 (1.00) | CES2CES1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453974-A | TREATMENT OF SEEDS OR SEEDLINGS | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | claimed |
| US-4371606-A | 2-(Halogenomethyl-phenyl)-4-halogeno-oxaxole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| US-4228082-A | FUNGICIDES OR CHEMICAL INTERMIDIATES FOR 1,2,4-TRIAZINONE HERBICIDES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-10-14 | — | — | US | disclosed |
| US-4224226-A | FUNGICIDES BY CONDENSING AN ACYL CYANIDE WITH EITHER A TERTIARY ALCOHOL OR AN ALKENE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-23 | — | — | US | disclosed |