Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038132 | 0.88 | TDP1 (0.60) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11038773 | 0.87 | TDP1 (0.63) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11133460 | 0.86 | TDP1 (0.43) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11125702 | 0.85 | TDP1 (0.63) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL5953095 | 0.84 | TDP1 (0.70) | TDP1RORCKMT2AMEN1CYP1A2 | |
| SCHEMBL11040406 | 0.84 | TDP1 (0.55) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11042456 | 0.82 | TDP1 (0.53) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11054773 | 0.81 | MTNR1A (0.40) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL11038744 | 0.79 | HDAC3 (0.51) | TDP1RORCMTNR1AMTNR1BKMT2A | |
| SCHEMBL13763482 | 0.76 | TDP1 (0.70) | TDP1RORCKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984000032-A1 | AMINO-OXY-(MERCAPTO-ALKYL)-BENZENES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL PRODUCTS CONTAINING THEM | SANDOZ AG (CH) | 1984-01-05 | — | — | WO | disclosed |