Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.79 |
| ▸ | PPARD | Q03181 | 2/20 | 0.79 |
| ▸ | PPARA | Q07869 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.77 |
| ▸ | CYSLTR1 | Q9Y271 | 15/20 | 0.77 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369990 | 0.88 | PPARG (1.00) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL2067483 | 0.88 | PPARG (1.00) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL10695725 | 0.88 | PPARG (0.68) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL3894010 | 0.86 | PPARG (0.80) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL10744397 | 0.86 | GRM2 (0.95) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11046915 | 0.85 | PPARG (0.74) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11044280 | 0.85 | CYSLTR2 (0.78) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL5638968 | 0.85 | PPARG (0.77) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL10556919 | 0.85 | PPARG (0.77) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL10742441 | 0.85 | PPARG (0.67) | PPARGPPARDPPARALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028063-B1 | PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-06-13 | — | — | EP | disclosed |
| EP-0028063-A1 | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-06 | — | — | EP | disclosed |