Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040310 | 0.83 | CA2 (0.51) | CA2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11041960 | 0.82 | CA2 (0.60) | CA2HTR2CHSD11B1 | |
| SCHEMBL11043516 | 0.80 | CA2 (0.62) | CA2KMT2AUSP2L3MBTL1ALDH1A1 | |
| SCHEMBL11039051 | 0.79 | CA2 (0.60) | CA2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11040511 | 0.79 | CA2 (0.60) | CA2ALDH1A1MAPTHTR2CLMNA | |
| SCHEMBL11043198 | 0.78 | CA2 (0.58) | CA2L3MBTL1ALDH1A1KDM4EHTR2C | |
| SCHEMBL11040351 | 0.78 | CA2 (0.50) | CA2KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL11040233 | 0.78 | CA2 (0.59) | CA2ALDH1A1MAPTHTR2CLMNA | |
| SCHEMBL11040237 | 0.78 | CA2 (0.59) | CA2ALDH1A1MAPTHTR2CLMNA | |
| SCHEMBL10893526 | 0.77 | CA2 (0.55) | CA2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454320-A | Process for 5-substituted dialuric acids | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |