SCHEMBL1104393

SCHEMBL1104393

COc1ccc(-c2nnc(S)n2CCc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
ALDH1A1 P00352 8/20 0.52
KDM4E B2RXH2 6/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
NPSR1 Q6W5P4 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 4/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 2/20 0.45
CNR2 P34972 1/20 0.45
USP2 O75604 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104386 0.86 ALDH1A1 (0.59) MAPTALDH1A1KDM4EHPGDNPSR1
SCHEMBL1104397 0.86 SMN1; SMN2 (0.50) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1104328 0.86 MEN1 (0.51) MAPTALDH1A1SMN1; SMN2TP53TSHR
SCHEMBL1104358 0.82 TP53 (0.55) MAPTALDH1A1HPGDHSD17B10NPSR1
SCHEMBL1104365 0.82 MEN1 (0.46) ALDH1A1KDM4EHSD17B10SMN1; SMN2TP53
SCHEMBL14557019 0.82 MEN1 (0.43) MAPTALDH1A1SMN1; SMN2TP53NPC1
SCHEMBL11511994 0.82 ALDH1A1 (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL14559345 0.82 MEN1 (0.47) MAPTALDH1A1HPGDSMN1; SMN2TP53
SCHEMBL10480384 0.82 TMEM97 (0.48) ALDH1A1KDM4ESMN1; SMN2TSHRRAB9A
SCHEMBL12110686 0.80 SSTR4 (0.45) MAPTALDH1A1SMN1; SMN2TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1906245-B1 Photopolymerization type photosensitive lithographic printing plate precursor FUJIFILM CORP (JP) 2013-02-27 EP disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed