Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615894 | 1.00 | TSHR (0.44) | TSHRSMPD1FDPSALDH1A1THRB | |
| SCHEMBL9681934 | 1.00 | TSHR (0.44) | TSHRSMPD1FDPSALDH1A1THRB | |
| SCHEMBL9463177 | 1.00 | TSHR (0.44) | TSHRSMPD1FDPSALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11722444 | 0.98 | TSHR (0.43) | TSHRSMPD1FDPSALDH1A1THRB | |
| Bromide SCHEMBL29216856 | 0.98 | TSHR (0.43) | TSHRSMPD1FDPSALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11578293 | 0.98 | TSHR (0.43) | TSHRSMPD1FDPSALDH1A1THRB | |
| SCHEMBL3237803 | 0.98 | TSHR (0.41) | TSHRSMPD1FDPSALDH1A1THRB | |
| SCHEMBL9245821 | 0.91 | TSHR (0.40) | TSHRFDPSALDH1A1 | |
| SCHEMBL9701841 | 0.90 | SMPD1 (0.40) | TSHRSMPD1FDPSALDH1A1TNNC1 | |
| Bromide SCHEMBL9850859 | 0.89 | TSHR (0.39) | TSHRFDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543411-A | RUTHENIUM CONTAINING CATALYST MIXED WITH PHOSPHONIUM SALT | TEXACO INC. (US) | 1985-09-24 | — | — | US | disclosed |