Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245821 | 0.98 | TSHR (0.40) | TSHRALDH1A1FDPS | |
| Bromide SCHEMBL29216856 | 0.91 | TSHR (0.43) | TSHRALDH1A1FDPS | |
| SCHEMBL3237803 | 0.91 | TSHR (0.41) | TSHRALDH1A1FDPS | |
| SCHEMBL28615894 | 0.89 | TSHR (0.44) | TSHRALDH1A1FDPS | |
| SCHEMBL9681934 | 0.89 | TSHR (0.44) | TSHRALDH1A1FDPS | |
| SCHEMBL11043945 | 0.89 | TSHR (0.44) | TSHRALDH1A1FDPS | |
| SCHEMBL9463177 | 0.89 | TSHR (0.44) | TSHRALDH1A1FDPS | |
| Hydrochloric Acid SCHEMBL11722444 | 0.87 | TSHR (0.43) | TSHRALDH1A1FDPS | |
| Hydrochloric Acid SCHEMBL11578293 | 0.87 | TSHR (0.43) | TSHRALDH1A1FDPS | |
| SCHEMBL2787839 | 0.83 | TSHR (0.35) | TSHRALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416427-A1 | Neutral sizing agent for rough paper masses using cationic polymer dispersions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-13 | — | — | EP | disclosed |