SCHEMBL1104400

SCHEMBL1104400

Sc1nnc(-c2ccccc2)n1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
KDM4E B2RXH2 4/20 0.50
TSHR P16473 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PDE6D O43924 1/20 0.50
ALDH2 P05091 1/20 0.50
ALDH3A1 P30838 1/20 0.50
LMNA P02545 5/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 3/20 0.49
HPGD P15428 2/20 0.49
RAB9A P51151 2/20 0.46
RECQL P46063 1/20 0.46
CASP3 P42574 1/20 0.44
NR1H3 Q13133 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14160787 0.91 KDM4E (0.50) ALDH1A1KDM4ETSHRNPSR1PDE6D
SCHEMBL1104402 0.90 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRNPSR1PDE6D
SCHEMBL10011649 0.90 KDM4E (0.60) ALDH1A1KDM4ETSHRNPSR1LMNA
SCHEMBL1104378 0.90 ALDH1A1 (0.54) ALDH1A1KDM4ETSHRNPSR1PDE6D
SCHEMBL1104406 0.89 MEN1 (0.55) ALDH1A1KDM4ETSHRNPSR1PDE6D
SCHEMBL10480335 0.89 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRNPSR1PDE6D
SCHEMBL6404288 0.88 ALDH1A1 (0.58) ALDH1A1KDM4ETSHRNPSR1LMNA
SCHEMBL10432075 0.86 ALDH1A1 (0.56) ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1
SCHEMBL1104417 0.86 ALDH1A1 (0.56) ALDH1A1KDM4ETSHRNPSR1LMNA
SCHEMBL1104401 0.85 ALDH1A1 (0.43) ALDH1A1KDM4ETSHRNPSR1PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1989006125-A1 4-ARALKYL-5-SUBSTITUTED-1,2,4-TRIAZOLE-5-THIOLS SMITHKLINE BECKMAN CORPORATION (US) 1989-07-13 WO claimed
EP-0323737-A1 4-Aralkyl-5-substituted-1,2,4-triazole-5-thiols SMITHKLINE BEECHAM CORPORATION (US) 1989-07-12 EP claimed
EP-2131239-B1 Processing liquid for lithographic printing plate development and method of producing lithographic printing plates FUJIFILM CORP (JP) 2016-03-23 EP disclosed
EP-2141206-B1 Novel compound, polymerizable composition, color filter and production method thereof, solid-state imaging device, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-12-03 EP disclosed
US-8846277-B2 Compound, polymerizable composition, color filter, and method of producing the same, solid-state imaging device, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8846277-B2 Compound, polymerizable composition, color filter, and method of producing the same, solid-state imaging device, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8703366-B2 2014-04-22 US disclosed
US-8703366-B2 2014-04-22 US disclosed
EP-2128704-B1 Processing Liquid for Lithographic Printing Plate Development and Method of Producing Lithographic Printing Plates FUJIFILM CORP (JP) 2013-06-05 EP disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070048663-A1 Photopolymerizable photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
WO-1989006125-A1 4-ARALKYL-5-SUBSTITUTED-1,2,4-TRIAZOLE-5-THIOLS SMITHKLINE BECKMAN CORPORATION (US) 1989-07-13 WO disclosed
EP-0323737-A1 4-Aralkyl-5-substituted-1,2,4-triazole-5-thiols SMITHKLINE BEECHAM CORPORATION (US) 1989-07-12 EP disclosed