Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046838 | 0.93 | NR1I2 (0.30) | NR1I2PGR | |
| SCHEMBL10857288 | 0.90 | KCNH2 (0.36) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10935306 | 0.89 | NR1I2 (0.35) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11040791 | 0.87 | NR1I2 (0.40) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11012770 | 0.86 | TDP1 (0.47) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10838521 | 0.85 | KCNH2 (0.42) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10829502 | 0.85 | NR1I2 (0.39) | TDP1TSHRAPEX1PSMD14MMP2 | |
| SCHEMBL10858019 | 0.84 | KCNH2 (0.36) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10850531 | 0.84 | KCNH2 (0.35) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10836934 | 0.84 | NR1I2 (0.40) | TDP1LMNAAPEX1L3MBTL1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | claimed |
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |