Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 9/20 | 0.33 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048029 | 0.93 | NR1I2 (0.38) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10939452 | 0.88 | NR1I2 (0.46) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL11044057 | 0.87 | TDP1 (0.32) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL11004980 | 0.85 | NR1I2 (0.57) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10840189 | 0.84 | NR1I2 (0.42) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL9660164 | 0.83 | NR1I2 (0.39) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL11011011 | 0.83 | NR1I2 (0.46) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL10937425 | 0.82 | NR1I2 (0.43) | NR1I2PGRTDP1APAF1APEX1 | |
| SCHEMBL11357586 | 0.82 | NR1I2 (0.49) | NR1I2PGRTDP1APEX1LMNA | |
| SCHEMBL10854742 | 0.82 | NR1I2 (0.41) | NR1I2PGRTDP1APAF1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | claimed |
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |